The symptoms of hepatitis A appear no earlier than 60 days after a person has been infected. In a test of a hepatitis A vaccine, 50 people received the vaccine and 50 people received a harmless placebo. Although some people from each group eventually exhibited symptoms of hepatitis A, the vaccine as used in the test is completely effective in preventing infection with the hepatitis A virus.
Which one of the following, if true, most helps resolve the apparent discrepancy in the information above?
Show answer and explanation
Correct answer: D
For Q. 10 we need to resolve the apparent discrepancy. Remember, the first step in this question type is to make sure you understand, in your own words, the nature of the discrepancy before moving on to the answer choices. In this case, the discrepancy is signaled by the Keyword "although" in the last sentence.
The paradox is that even though the vaccine used in this test is completely effective in preventing hepatitis, members of both groups exhibited symptoms of hepatitis A. Now, it's not surprising that members of the placebo group may have contracted the disease; after all, they weren't vaccinated. But how could the
members of the group that received the vaccine exhibit symptoms of hepatitis if we're told the vaccine is completely effective in preventing it? Try to answer that yourself, and then look to the answer choices for a similar explanation. Option [The vaccinated people who...] is correct because it gives a perfectly logical explanation: the people who exhibited symptoms contracted hepatitis before they were vaccinated.
Remember, the stimulus tells us that the symptoms appear no earlier than 60 days after a person has been infected. Therefore, if a person were infected on day 1, and received the vaccine on day 10, we would expect that person to exhibit symptoms sometime after he or she was vaccinated.