NABP NABP Certifications FPGEE Questions & Answers

• Question 111:

  Atropine poisoning can be recognized by all of the following signs or symptoms, EXCEPT:

  A. dry skin

  B. flushed appearance

  C. delirium and restlessness

  D. mydriasis

  E. diarrhea

  Correct Answer: E

• Question 112:

  The organophosphates commonly found in insecticides are thought to act by which of the following mechanisms?

  A. Combining with acetylcholine

  B. Potentiating the action of acetylcholinesterase

  C. Forming a very stable complex with acetylcholinesterase

  D. Reacting at the cholinergic receptor

  E. Preventing the release of acetylcholine from the nerve ending

  Correct Answer: C

• Question 113:

  The skeletal structure of the hipbone includes the:

  I ilium II ischium III pubis

  A. I only

  B. III only

  C. I and II only

  D. II and III only

  E. I, II and III

  Correct Answer: E

• Question 114:

  Which of the following statements is FALSE regarding tablet formulation?

  A. Diluents are fillers to add bulk to the tablet.

  B. Lubricants help the patient to swallow the tablet more easily.

  C. Binding agents may be added dry or in solution.

  D. Disintegrants draw water into the tablet causing it to burst.

  E. Glidants promote the flow of materials during compression.

  Correct Answer: B

• Question 115:

  Structure-activity studies of cholinergic drugs indicate that:

  I. maximum activity is achieved when the quaternary nitrogen is three carbons removed from the ester oxo group.

  II. structures which display a quasi-ring conformation exhibit muscarinic activity.

  III.

  one methyl group of the trimethylammonium group can be replaced by an ethyl group with only slight loss of activity.

  A.

  I only

  B.

  III only

  C.

  I and II only

  D.

  II and III only

  E.

  I, II and III

  Correct Answer: D

• Question 116:

  Which of the following is an azo dye?

  A. Hexachlorophene

  B. Nitrofurantoin

  C. Methenamine

  D. Phenazopyridine

  E. Nalidixic acid

  Correct Answer: D

• Question 117:

  If the total body clearance of a drug is 200 mL/min in a normal healthy adult and the renal clearance is 10 mL/ min then one may assume that:

  A. the drug is extensively metabolized.

  B. greater than normal drug accumulation would occur in patients with moderate renal failure.

  C. entero-hepatic recycling is significant.

  D. the drug is not bound to plasma proteins.

  E. the drug is concentrated in adipose tissue.

  Correct Answer: A

• Question 118:

  Approximately 50% of dicloxacillin is excreted unchanged in the urine. If the normal dosage schedule for dicloxacillin is 125 mg q6h, a patient with renal function 20% of normal should receive:

  A. 25 mg q6h

  B. 31.25 mg q6h

  C. 62.5 mg q6h

  D. 75 mg q6h

  E. 125 mg q12h

  Correct Answer: D

• Question 119:

  Carbon monoxide binds to:

  I hemoglobin II myoglobin III cytochrome oxidase

  A. I only

  B. III only

  C. I and II only

  D. II and III only

  E. I, II and III

  Correct Answer: E

• Question 120:

  Antioxidants, which mechanistically act as reducing agents, include:

  I ascorbic acid II sodium bisulfite III citric acid

  A. I only

  B. III only

  C. I and II only

  D. II and III only

  E. I, II and III

  Correct Answer: C