ASCP ASCP-MLT Online Practice Questions and Exam Preparation

ASCP ASCP-MLT Online Questions & Answers

• Question 401:

  Which of the following tubes produces a serum sample? Question options:

  A. green
  B. pink
  C. tiger (red-gray)
  D. blue
  C. tiger (red-gray)

• Question 402:

  Which of the following genotypes cause beta thalassemia minor?

  A. B/B
  B. B+/B
  C. B0/B
  D. B0/B0
  B. B+/B

• Question 403:

  Provide the equivalent measurement for one gallon.

  Question options:

  A. 3.79 liters
  B. 1 liter
  C. 2.5 liters
  D. 4.2 liters
  A. 3.79 liters

• Question 404:

  The Bethesda assay is used to measure the titer and activity of the antibody present in a patient's sample. Prothrombin time is an initial screening procedure for bleeding disorders and a test used for monitoring anticoagulant therapy. A

  thrombin time is used to detect heparin interference in an aPTT mixing study. A mixing study is performed to detect the presence of a factor deficiency or coagulation inhibitor, but does not quantify the result.

  Hematology

  Which of the following tests is used to quantify a coagulation inhibitor?

  A. Prothrombin time
  B. Thrombin time
  C. Mixing study
  D. Bethesda assay
  C. Mixing study

• Question 405:

  Which immune elements are involved in a POSITIVE TB skin test?

  A. IgE T cells and macrophages
  B. Nkcells and IgG antibodies
  C. B cells and IgM antibodies
  D. Epithelial skin cells
  C. B cells and IgM antibodies

• Question 406:

  The proper pH for a unit of platelets must be above 6.2. According to the FDA, accurate pH measurement is time dependent, and samples should be tested within 1 hour of sampling, or as suggested by the manufacturer of the pH measurement system. It is recommended that a pH meter or gas analyzer be routinely used rather than pH (nitrazine) paper. However, if the laboratory chooses to determine pH measurements with nitrazine paper, the selected paper should read in increments of one-tenth units, or it may provide inaccurate measurements. Maintaining proper pH requires at least 35 ml, but preferably 50- 70 ml of plasma per platelet unit.

  In order to prevent a loss of viability in platelet concentrates during storage the pH must be maintained above:

  A. 7.5
  B. 6.2
  C. 5.0
  D. 4.5
  B. 6.2

• Question 407:

  A quality control program is to be set up for the following tests:

  Phenylalanine deaminase (PAD)

  Indole production

  Voges-Proskauer (V-P)

  Which pair of stock culture organisms would be MOST suitable to verify the performance of these three tests?

  A. vulgaris, Escherichia coli Klebsiella pneumonia, Proteus vulgaris
  B. coli, Enterobacter aerogenes
  C. aerogenes, K. pneumonia Bacillus anthracis, Yersinia pestis
  A. vulgaris, Escherichia coli Klebsiella pneumonia, Proteus vulgaris

• Question 408:

  Beta-thalassemia major, also known as Cooley's anemia, has inherited two genes for beta thalassemia without a normal beta-chain gene. This disease is assoicated with a marked deficiency in beta chain production and in the production of

  normal Hb A. These patients exhibit increased amounts of iron due to the mutliple transfusions that keep them alive. There is also a striking increase in hemoglobin F and an elevation in hemoglobin A2.

  Hematology

  A 5-year-old African American child with hepato-splenomegaly and skeletal abnormalities has the following lab results:

  WBC = 4,800/cu.mm

  20 NRBC/100 WBC

  RBC = 2.70 X 106

  HGB = 6.2 g/dL

  Many target cells

  Marked hypochromasia, anisocytosis and poikilocytosis Serum Iron = 200 μg/dL (elevated) Sickle Solubility = negative

  Hemoglobin F = elevated

  What is the PROBABLE cause of these findings?

  A. Aplastic anemia
  B. Beta-thalassemia major
  C. Sickle cell anemia
  D. Hemoglobin C disease
  B. Beta-thalassemia major

  ---

  Explanation/Reference:

• Question 409:

  Which method remains the "gold standard" for ANA detection?

  A. Radioimmunoassay (RIA)
  B. Lateral Flow Immunoassay
  C. Enzyme Immunoasay (ELISA)
  D. Slide-based immunofluorescent assay (IFA) or Colorzyme
  D. Slide-based immunofluorescent assay (IFA) or Colorzyme

• Question 410:

  Neutrophils reside in the peripheral circulation for only 7-8 hours ( approx. 7.5 hours) before entering the tissues and body cavities. This process is called diapedesis.

  Hematology

  How long are healthy neutrophils expected to reside in the peripheral blood of an adult?

  A. 3 days
  B. 1 day
  C. 7-8 hours
  D. 12-14 hours
  C. 7-8 hours