NABP NABP Certifications NAPLEX Questions & Answers

• Question 101:

  What is the Osmolarity in mOsm/L of 40mEq of KCl in 100ml sterile water? (Molecular weight of KCl is 74.5gm/mol.)?

  A. 400mOsm/L

  B. 800mOsm/L

  C. 80mOsm/L

  D. 200mOsm/L

  E. 1600mOsm/L

  Correct Answer: B

• Question 102:

  Which of the following is/are ordinal data?

  A. NYHA I-IV

  B. Grade of breast cancer

  C. Sex

  D. Improvement Yes/No

  E. Alive or Dead

  Correct Answer: B

  Categorical data includes ordinal (ordered categories) and nominal (unordered categories). NYHA I-IV and grade of breast cancer are considered ordinal data because the categories for the answer choice are in order, you can have NYHA class I, II, III, or IV. Grade of breast cancers are also in order, grade 1, 2, or 3. Sex, Improvemnet Yes/No, Alive or Dead is considered nominal, unordered data because the answer choices are female or male, and do not have a set order.

  Reference: http://www.bmj.com/about-bmj/resources-readers/publications/statistics-square-one

• Question 103:

  All of the following may increase triglycerides except:

  A. Protease inhibitor

  B. Bile acid sequestrants

  C. Fish oil

  D. Oral estrogens

  E. Glucocorticoids

  Correct Answer: C

  Agents that can cause elevated triglycerides: oral estrogens, glucocorticoids, bile acid sequestrants, protease inhibitors, retinoic acid, anabolic steroids, sirolimus, raloxifene, tamoxifen, beta blockers (not carvedilol), and thiazides.

• Question 104:

  What is the mEq/ml (Milliequivalents) of 50% Magnesium Sulfate? (Molecular weight of MgSO4 is 120.4g/ mol.)

  A. 8.3mEq/ml

  B. 4.11mEq/ml

  C. 62mEq/ml

  D. 50mEq/ml

  E. 2.06mEq/ml

  Correct Answer: B

  50gm/100ml × 1equiv/120.4gm × 1000meq/1equiv = 4.16meq/ml

• Question 105:

  What is the weight of 1000 ml of serum protein whose specific gravity is 1.27?

  A. 1270 gm

  B. 127mg

  C. 12.7mg

  D. 12.7gm

  E. 1.27gm

  Correct Answer: A

  SG= weight/mL, 1.27 = x/1000ml, x = 1270gm

• Question 106:

  RL is a 54 YOM who's calculated 10-year atherosclerotic cardiovascular disease (ASCVD) risk is 18 %.

  Which of the following is the most appropriate pharmacotherapy recommendation for CR?

  A. Rosuvastatin 10 mg PO QHS

  B. Atorvastatin 80 mg PO QHS

  C. Lovastatin 10 mg PO QHS

  D. Pravastatin 20 mg PO QHS

  E. Atorvastatin 20mg PO QHS

  Correct Answer: B

  This patient belongs in one of the four statin benefit groups because his estimated 10-year ASCVD risk is over 7.5%. Adults 40 to 75 years of age with LDL–C 70 to 189 mg/dL, with an estimated 10-year ASCVD risk ≥7.5% and without clinical ASCVD or diabetes should receive either a moderate-intensity or high-intensity statin. Since the extent of reducing the risk of ASCVD is proportionally related to the degree of LDL-C reduction, risk could be reduced more so with a high intensity statin. Considering the given options, Atorvastatin 80 mg PO QHS is the best choice.

• Question 107:

  Which of the following is/are appropriate for pseudomonas skin/soft tissue infections?

  A. Ertapenem

  B. Cefepime

  C. Ceftaroline

  D. Cefazolin

  E. Vancomycin

  Correct Answer: B

  Ceftaroline covers MRSA, but it does not cover pseudomonas. Ertapenem does not cover pseudomonas. Cefazolin does not cover MRSA nor Pseudomonas. Cefepime has pseudomonas coverage. Vancomycin does not cover gram negative bacteria.

• Question 108:

  Injectable Sulfamethoxazole/Trimethoprim comes as 400mg/80mg/5ml. Physician requests you to dose a Sulfamethoxazole/Trimethoprim intravenously for PCP. You know the dose is 15mg/kg/day (based on TMP component) divided q6h.

  How many milliliters of Sulfamethoxazole/Trimethoprim of 400mg/80mg/5ml would you need for single dose? Patient weighs 80kg.

  A. 18.75 mL

  B. 75 mL

  C. 15 mL

  D. 50 mL

  E. 16.5 mL

  Correct Answer: A

  80kg person = 15mg/kg/day = 1200mg/day 80mg /5ml = 1200mg/X X= 75mL/day / 4 doses = 18.75 mL per dose

• Question 109:

  According to the 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to ReduceAtherosclerotic Cardiovascular Risk in Adults, which of the following LDL cholesterol thresholds is an indication for high-intensity statin therapy?

  A. 100 mg/dL

  B. 130 mg/dL

  C. 190 mg/dL

  D. 200 mg/dL

  E. 150 mg/dL

  Correct Answer: C

• Question 110:

  An order is received for heparin 18 units per kg per hour on a patient whose weight is 125lb. The IV bag comes as a concentration of 50 units /mL. Calculate the infusion rate in terms of mL/hr.

  A. 5.15 mls/hr

  B. 10.23 mls/hr

  C. 40.9 mls/hr

  D. 20.45 mls/hr

  E. 18 mls/hr

  Correct Answer: D