NABP NABP Certifications NAPLEX Questions & Answers

• Question 11:

  In the management of acute ischemic stroke, within how many minutes from symptom onset should alteplase be administered?

  A. 3 hours

  B. 6 hours

  C. 12 hours

  D. 24 hours

  Correct Answer: A

  In the management of acute ischemic stroke, alteplase should be administered within 3 hours of symptom onset.

• Question 12:

  What is the amount of potassium permanganate in 300mL of a 1 in 25 solution?

  A. 1 gram

  B. 8 grams

  C. 12 grams

  D. 14 grams

  Correct Answer: C

• Question 13:

  What is the active ingredient found in the medicine Adalat?

  A. Nifedipine

  B. Adalimumab

  C. Digoxin

  D. Simvastatin

  Correct Answer: A

• Question 14:

  Mesna is typically administered alongside which of these chemotherapeutic agents?

  A. Busulfan

  B. Paclitaxel

  C. Ifosfamide

  D. Doxorubicin

  Correct Answer: C

  Mesna is administered to patients taking either ifosfamide or cyclophoshamide to conjugate toxic acrolein and therefore prevent hemorrhagic cystitis (bladder bleeding).

• Question 15:

  What is the mechanism of action of the active ingredient found in Zyflo?

  A. Ultra-long-acting beta-2 agonist

  B. 5-lipogenase inhibitor

  C. Leukotriene D4 inhibitor

  D. Long-acting anticholinergic

  Correct Answer: B

  Zileuton is the active ingredient found in the medicine Zyflo; a medicine that works as a 5-lipoxygenase inhibitor. As such, zileuton inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, and is used for the maintenance treatment of asthma in patients older than the age of 12. In 2 percent of patients, it raises liver enzymes. Sinusitis and nausea are the most common side effects.

• Question 16:

  What is the standard oral weekly dose of alendronate given to treat osteoporosis?

  A. 10mg

  B. 70mg

  C. 140mg

  D. 200mg

  Correct Answer: B

  The standard oral dose of alendronate in the treatment of osteoporosis is 70mg weekly ?or 10mg per day.

• Question 17:

  A CD4 count of 180 cells per cubic meter may be evaluated as which of these?

  A. Very low

  B. Low

  C. High

  D. Severely high

  Correct Answer: A

  A CD4 count of 180 cells per cubic meter is considered very low ?typically an indicator that the patient has an immunocompromised state, such as AIDS. CD4 counts are a measure of healthy T-cell levels. The lower the count, the more susceptible the patient is to opportunistic infections. A normal range is between 500 and 1,500 cells.

• Question 18:

  How many kcal per gram does IV dextrose provide?

  A. 0.9 kcal/g

  B. 1.2 kcal/g

  C. 1.5 kcal/g

  D. 3.4 kcal/g

  Correct Answer: D

  IV dextrose provides 3.4 kcal/g.

• Question 19:

  A patient with acute pharyngitis caused by group A Streptococcus (strep throat) is allergic to penicillins (non-immediate type), which of the following is NOT recommended as treatment?

  A. Clindamycin

  B. Amoxicillin

  C. Cefalexin

  D. Clarithromycin

  Correct Answer: B

  Amoxicillin is a penicillin and so should be avoided in patients even with a non-immediate allergy. Acute treatment should be administered with one of the other listed options.

• Question 20:

  Which of these substances is not used as a compounding preservative?

  A. Benzalkonium chloride

  B. Lecithin

  C. Sodium benzoate

  D. Benzyl alcohol

  Correct Answer: B

  Lecithin is used as a surfactant, not as a preservative. All other listed substances may be used as a preservative in compounding.