NABP NABP Certifications NAPLEX Questions & Answers

• Question 1:

  Which of these is an example of postrenal acute kidney injury (AKI)?

  A. Benign prostatic hyperplasia

  B. Heart failure

  C. Dehydration

  D. Renal vein thrombosis

  Correct Answer: A

  Benign prostatic hyperplasia (BPH) is an example of postrenal acute kidney injury (AKI). Postrenal AKI, as the name suggests, involves an effect `post' or `beyond' the kidney, to problems that emerge downstream from the kidney. BPH is one such example of that. Other examples include kidney stones, bladder stones and bladder cancer.

• Question 2:

  What is the active ingredient of the medicine Lyrica?

  A. Tramadol

  B. Digoxin

  C. Valproate

  D. Pregabalin

  Correct Answer: D

  Pregabalin is the active ingredient of the medicine Lyrica; a drug used to treat epilepsy, neuropathic pain, fibromyalgia and generalized anxiety disorder (GAD).

• Question 3:

  Before use, which of the following products should be used to clean surfaces of a laminar flow hood?

  A. 95% ethyl alcohol

  B. 70% isopropyl alcohol

  C. Purified water

  D. Purified WFI

  Correct Answer: B

  Before each use, 70% isopropyl alcohol should be used to clean surfaces of a laminar flow hood.

• Question 4:

  A 49-year-old's blood test results have come back from the lab. Their chloride level currently measures 99 mEq/L. How should you interpret this result?

  A. Very low, requires immediate treatment

  B. Slightly below normal

  C. Within the normal range

  D. Very high, requires immediate treatment

  Correct Answer: C

  Serum chloride levels should ideally fall between 96-106 mEq/L. For this reason, the patient's chloride level has come back as normal.

• Question 5:

  How many millimoles of sodium are in 0.9% sodium chloride?

  A. 90 millimoles

  B. 99 millimoles

  C. 145 millimoles

  D. 154 millimoles

  Correct Answer: D

  0.9% = 9 grams per every 1,000mL Molecular weight of NaCl = 58.5 9 / 58.5 = 0.154 moles 0.154 moles is the same as 154 millimoles There are 154 millimoles of sodium ions and 154 millimoles of chloride ions in 0.9% sodium chloride.

• Question 6:

  The administration of dapsone gel for the topical treatment of acne vulgaris in patients with G6PD deficiency may produce which of these?

  A. Anaphylaxis

  B. Fungal infections

  C. Hemolysis

  D. Immunosuppression

  Correct Answer: C

• Question 7:

  A 51-year-old patient, who takes a calcium channel blocker (CCB), reports that he is experiencing constipation. Which CCB is the patient most likely to be taking?

  A. Nifedipine

  B. Amlodipine

  C. Verapamil

  D. Diltiazem

  Correct Answer: C

  Non-dihydropyridine calcium channel blockers ?which are diltiazem and verapamil ?are statistically more likely to cause constipation. Of these two, verapamil has a higher probability of causing this side effect.

• Question 8:

  A patient presents in the pharmacy in a delirious state with pinpoint pupils. Which of the following toxicity states does the patient most likely have?

  A. Alcohol

  B. Opioid

  C. Benzodiazepine

  D. Amphetamine

  Correct Answer: B

  Signs of opioid overdose include pinpoint pupils, delirious state, nausea / vomiting, respiratory depression and sleepiness or loss of consciousness. Naloxone may be used to reverse the effects of opioid overdose.

• Question 9:

  Which of these medicines is well-known to cause a positive direct Coombs test?

  A. Methyldopa

  B. Labetalol

  C. Hydralazine D. Nifedipine

  Correct Answer: A

• Question 10:

  Which H2-receptor blocker may cause gynecomastia in men due to its antiandrogenic effects?

  A. Ranitidine

  B. Nizatidine

  C. Cimetidine

  D. Famotidine

  Correct Answer: C

  Cimetidine has multiple drug interactions due to its inhibitory effects on CYP1A2, 2C9, 2D6, and 3A4. Inhibition of these enzymes can cause an increase in the serum concentrations of drugs metabolized by these enzymes, leading to toxicity.