ASCP ASCP Certifications ASCP-MLT Questions & Answers

• Question 211:

  Monoclonal antibodies are monospecific antibodies that are the same because they are made by one type of immune cell which are all clones of a unique parent cell, also called a hybrid cell line, which usually arise from a hybridoma. The fusion of a specific antibody- producing lymphocyte with a myeloma cell will multiply to become a source of pure monoclonal antibody. This is often used in the manufacturing process for monoclonal antibody reagents.

  Monoclonal antibodies are usually manufactured in vitro by using:

  A. Cultured T cells

  B. Human plasma cells

  C. Hybridomas

  D. Cytotoxic T cell

  Correct Answer: C

• Question 212:

  Which of the following fields is NOT an aspect of clinical microbiology?

  A. virology

  B. bacteriology

  C. pathology

  D. parasitology

  Correct Answer: C

• Question 213:

  This type of laboratory professional is responsible for the technical aspects of managing the operation of the laboratory and is most likely an MLS with additional education in administration:

  A. Laboratory Director

  B. Laboratory Manager

  C. Pathologist

  D. Laboratory Technologist

  Correct Answer: A

• Question 214:

  Oxalate, EDTA, and citrate are anticoagulants that inhibit clot formation.

  Which of the following blood additives is most useful for serum collection:

  A. Polymer barrier

  B. Oxalate

  C. EDTA

  D. Citrate

  Correct Answer: A

• Question 215:

  A normal hemoglobin molecule consists of a tetramer, of four heme and four globin chains, with a molecular weight of 64,500 daltons. Each of the four units can bind a molecule of oxygen for transport to the body's tissues. In the image shown below, there are four monomers (2 red globin chains and 2 blue globin chains) which form the entire hemoglobin tetramer structure. The green portions represent the 4 heme groups.

  A normal hemoglobin molecule is comprised of the following:

  

  A. Ferrous iron and four globin chains

  B. Four heme and four globin chains

  C. Four heme and one globin chains

  D. One heme and four globin chains

  Correct Answer: B

• Question 216:

  The identification of the crystals depicted in this image are triple phosphate crystals. Triple phosphate crystals may be normal but are usually associated with alkaline urine. These colorless crystals have a characteristic "coffin lid" appearance.

  

  What is the identification of these crystals seen in urine with an alkaline pH?

  A. Uric acid

  B. Calcium oxalate

  C. Triple phosphate

  D. Calcium carbonate

  Correct Answer: C

• Question 217:

  In the laboratory, surfaces must be disinfected for blood spills. What is the most common disinfectant used?

  A. A dilution of 5.2% sodium hypochlorite solutionCorrect

  B. 2% saline

  C. 25% ethanol

  D. Distilled water

  Correct Answer: A

• Question 218:

  AHG must be added to the cells immediately following washing. Antibodies may elute from the cells if the cells are allowed to sit in saline without the addition of AHG. Which one of the following may cause a FALSE-NEGATIVE result with antiglobulin techniques?

  A. Red cell/AHG test sample is over-centrifuged

  B. Patient's blood specimen was collected in silicone gel tubes

  C. Saline used for washing the test sample has been stored in squirt bottles

  D. Addition of AHG is delayed for 40 minutes or more after final saline wash

  E. Patient's red cells have an antibody coating them

  Correct Answer: D

• Question 219:

  hs-CRP is a recent marker of chronic inflammation. New measurements of CRP in lower levels (hs-CRP) are now measured to monitor risk of cardiovascular disease.

  Select the statement that best describes hs-CRP?

  A. hs-CRP is a measurement of acute inflammation and is used to monitor these conditions

  B. hs-CRP is an anti-inflammatory adipokine synthesized by adipocytes

  C. hs-CRP is a marker of chronic inflammation and measured to predict the risk of cardiovascular disease

  D. hs-CRP is decreased in inflammatory conditions and measured to predict a return of inflammation

  Correct Answer: C

• Question 220:

  Waived tests are those considered to have an insignificant risk of erroneous results. Which of the following is NOT an example of a waived test?

  A. rapid strep tests from throat swabs

  B. sodium

  C. HIV antibodies

  D. prothrombin time

  Correct Answer: B