Which of the following drugs could be the cause of SM's complaints?
A. Bismuth subsalicylate
B. Cotrimoxazole
C. Doxycycline
D. Amoxicillin
E. Loperamide
Organisms commonly implicated in the cause of Trave||er's Diarrhea include:
I. Bacteroides fragilis
II. Escherichia coli
III.
Shigella sp
A.
I only
B.
III only
C.
I and II only
D.
II and III only
E.
I, II and III
Drugs shown to be effective in the prevention of Travellers' Diarrhea, which might have been prescribed for SM include:
I. doxycycline
II. cotrimoxazole
III.
amoxicillin
A.
I only
B.
III only
C.
I and II only
D.
II and III only
E.
I, II and III
In an adequately powered, randomized controlled trial conducted over 3 years, a specific serious side effect (i.e. reduction in leukocytes) with conventional therapy is seen in 0.5% of the study sample. In patients who receive a newly discovered drug, only 0.45% experience the same side effect. Based on these results, the minimum number of patients that would have to receive the new drug for 3 years to statistically demonstrate the prevention of one episode of this side effect in at least one patient is:
A. 15.
B. 20.
C. 150.
D. 200.
E. 2000.
The pharmacist fills a prescription for sumatriptan 100 mg tablets for a migraine patient. Appropriate information to provide to the patient includes which of the following?
A. If the sumatriptan does not relieve the headache within four hours, ergotamine may be used.
B. If no relief is achieved in two hours, sumatriptan may be repeated.
C. If the headache is relieved but another headache occurs eight hours later, sumatriptan may be used for the second headache.
D. The maximum dosage in any 24 hour period is six tablets.
E. If relief is not achieved, no other medication can be used for 24 hours.
Auxiliary labels which should be used on cotrimoxazole suspension include which of the following?
I. Shake well before using
II. Take with plenty of fluids
III.
Exposure to sunlight may cause adverse reactions
A.
I only
B.
III only
C.
I and II only
D.
II and III only
E.
I, II and III
A patient purchasing sublingual nitroglycerin tablets should be told to store the medication:
A. in the refrigerator
B. in a plastic vial with a childproof cap
C. with the original cotton
D. in an amber glass bottle with a metal cap
E. in a warm, dry place
Factors that determine bioalence of two brands of a drug include:
I. the taste of the preparations
II. the physical appearance of the preparations
III.
pharmacokinetic parameters of the preparations
A.
I only
B.
III only
C.
I and II only
D.
II and III only
E.
I, II and III
The style of management in which the owner of a pharmacy emphasizes the development of detailed policies and written procedures for employees to observe at all times is referred to as:
A. autocratic
B. bureaucratic
C. participative
D. benevolent
E. consultative
The shock and ainrvay edema of anaphylaxis are best treated with:
A. salbutamol
B. diphenhydramine
C. adrenaline
D. acetazolamide
E. aminophylline
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