Which of the following drugs is associated with the reaction of extreme photosensitivity?
A. Digitalis
B. Niacin
C. Tetracycline
D. Fluoroquinolones
Which of the following is not related to a drug toxicity of Prednisone?
A. Cataracts
B. Hypotension
C. Psychosis
D. Acne
Which of the following is not related to a drug toxicity of Atenolol?
A. CHF
B. Tachycardia
C. AV block
D. Sedative appearance
Which of the following is considered a class IA Sodium Channel blocker?
A. Mexiletine
B. Aminodarone
C. Quinidine
D. Procainamide
Which of the following enzymes could metabolize ethanol?
A. Cytochrome P450
B. Alcohol Dehydrogenase
C. Glucuronyl Transferase
D. Sulfotransferase
E. All of the above
Which of the following are similarities between Cytochrome P450 and MAO?
A. Both add oxygen from O2 to substrates and also form water
B. Both carry out direct heteroatom oxidations
C. Both carry out oxidative deaminations
D. Both carry out N-dealkylations
E. All of the above
What would be the preferred route of metabolism of succinyl choline?
A. Ester hydrolysis
B. N-oxidation
C. Glucuronide conjugation
D. A and B
E. All of the above
Which of the following causes the smallest change in solubility?
A. Hydroxylation
B. Glucuronidation
C. Sulfation
D. Glutathione conjugation
Cigarette smoke causes an increase in levels of CYP1A isozymes. Theophylline is primarily metabolized by the CYP1A system. What would happen to theophylline clearance for an asthmatic patient in hospital who could not smoke?
A. No change
B. Increase
C. Decrease
Which of the following is the antidote for the toxin Benzodiazepines?
A. Flumazenil
B. Methylene blue
C. Deferoxamine
D. Alkalinize urine
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