NABP NABP Certifications FPGEE Questions & Answers

• Question 361:

  Mechanism of action of flunisolide is:

  A. Inhibits DNA gyrase

  B. Inhibits phosphodiesterase

  C. Inhibits phospholipase A2

  D. beta-2 agonist

  E. Competitively inhibits H2 receptors

  Correct Answer: C

• Question 362:

  Mechanism of action of enalapril is:

  A. serotonin reuptake inhibitor

  B. Inhibits bone resorption

  C. beta-2 agonist

  D. Inhibits angiotensin converting enzyme

  E. lnduces "freezing" of initiation complex

  Correct Answer: D

• Question 363:

  Which of the following statements refers to HPMPC?

  A. Tricyclic.

  B. Cytosine monophosphate analog

  C. Works by accumulating in and changing pH of lysosomes.

  D. Mild intrinsic sympathomimetic activity - does not decrease heart rate and contractility as much during exercise.

  E. Metabolized in liver by P450.

  Correct Answer: B

• Question 364:

  Route of administration of interferon alpha is:

  A. Intramuscular

  B. Inhalation

  C. Topical

  D. Oral

  E. Intra-auricular

  Correct Answer: A

• Question 365:

  Side effect of clindamycin is:

  A. Colitis (by Chlostridium difficili)

  B. Malabsorption

  C. Constipation

  D. Hypoglycemia

  E. Hepatotoxicity

  Correct Answer: A

• Question 366:

  Indication of clindamycin is:

  A. Benzodiazepine intoxication

  B. Hypercalcemia

  C. Kaposi's sarcoma

  D. Streptococcus pneumoniae

  E. Angina

  Correct Answer: D

• Question 367:

  Indication of phenoxybenzamine is:

  A. Pain

  B. IVIovement disorders

  C. Thyrotoxicosis - preparation for radioactive iodine therapy

  D. Anaphylactic shock

  E. Acute hypertension

  Correct Answer: E

• Question 368:

  Which of the following statements refers to buspirone?

  A. Fatal overdosage rare unless taken with alcohol or other CNS depressants.

  B. Choice between quinidine and disopyramide should be made based on side effects. In patients with AV conduction problems or quinidine-induced GI toxicity, disopyramide ought to be chosen. In patients with MI or anticholinergic side effects, quinidine is the agent of choice.

  C. Less effective than tricyclics or ECT in unipolar depression.

  D. Is metabolized to several substances with long (>24 hours) half lives. These do not contribute to anticonvulsant effect but do contribute to sedative effect.

  E. No difference in effects between elderly and average population

  Correct Answer: E

• Question 369:

  Half-life of streptomycin is:

  A. 10-50 hours

  B. 8 hours

  C. 1 hour

  D. 16 hours

  E. 3-4 hours

  Correct Answer: E

• Question 370:

  Interactions with other drugs of clonazepam is:

  A. Lactose: increases absorption

  B. meperidine

  C. Tricyclic antidepressants: potentiate sedation

  D. cis-platinum - augments nephrotoxicity

  E. Oral contraceptives: inhibit metabolism

  Correct Answer: E