Which of the following statements refers to foscavir?
A. Pyrophosphate analog
B. Metabolism in liver is by glucuronidization
C. Not shown to reduce sudden death or prolong sunrival.
D. Inhibition of DNA gyrase results in:
1. Inhibition of bacterial replication 2. Inhibition of DNA repair 3. Inhibition of expression of certain operons
E. Non-nucleoside reverse transcriptase inhibitor
Indication of sodium valproate is:
A. Prophylaxis of certain infections
B. Partial complex seizures
C. Bipolar disorder
D. Delirium tremor
E. Primary immunodeficiency
Mechanism of action of carbenicillin is:
A. Inhibits transpeptidase
B. Blocks Na channels
C. Activates heparin cofactor II which inhibits thrombin (at high concentrations)
D. Blocks sustained repetitive neuronal firing
E. GM-CSF
Which of the following statements refers to flunisolide?
A. Penetrates placenta less readily than MMI
B. Causes fetal complications more frequently than PTU.
C. Is not as effective for acute attacks as beta-2 agonists.
D. Used only for maintenance/prophylaxis. Systemic steroids are used in case of acute exacerbations.
E. Cigarette smoking increases metabolism. Liver failure - decreases metabolism.
Cephalosporin mechanism of action may include:
A. Inhibit protein synthesis
B. Inhibit cell wall synthesis
C. Inhibit synthesis of essential metabolites
D. Alter the function of cell membrane permeability
E. Inhibit translation of genetic information
Class of tocainide is:
A. Thiazides
B. Antiarrhythmic agents
C. Cephalosporins
D. Autonomic nervous system drugs
E. Beta blockers
Route of administration of erythromycin is:
A. Inhalation
B. IV
C. Sublingual
D. Intra-auricular
E. Oral
Half-life of tolbutamide is:
A. 12-24 hours
B. 3 hours
C. 6-12 hours
D. 10 hours
E. 8 hours
Which of the following statements refers to fansidar?
A. Effect monitored by PT (prothrombin timE.
B. Embryopathy is due to production of epoxide metabolites. It is especially common when several anticonvulsants are used together.
C. Is a mixture of trimethoprim and sulfamethoxazole
D. Minimal GI absorption.
E. Allergic reactions (cutaneous) can be fatal in 1/20,000 users.
Indication of diazepam is:
A. Migraine prophylaxis
B. Bipolar disorder
C. Myoclonic seizures
D. Thyrotoxicosis - preparation for surgery
E. Trigeminal neuralgia
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