Resistance is the major problem with penicillins due to ability of bacteria to breakdown the Iactam ring of penicillin and inactivates the drug. To overcome these problem penicillins can be administrated together with -| actamase inhibitors. Examples of -|actamase inhibitors is/are:
I- Clavulanic acid II- Sulbactam III- Tazobactam
A. I only
B. III only
C. I and II only
D. II and III only
E. All are correct
Correct statements regarding CEPHALOSPORINS include:
I- Bactericidal antimicrobial II- Derivated from natural source: Cephalosporium acremonium III- Broad-spectrum agent
A. I only
B. III only
C. I and II only
D. II and III only
E. All are correct
Example of fourth generation cephalosporin includes:
A. Ceftriaxone
B. Cefipime
C. Cefixime
D. Cefotaxime
E. Cefoxitin
Correct statement regarding the mechanism of action of Vancomycin may include:
A. Inhibit release of tRNA bound to peptyl site after peptide bond formation
B. Inhibit peptide bound formation between acylaminoacids bound to the peptyl and acceptor site
C. Inhibit stage II of cell wall synthesis preventing polymerization of the linear peptideoglycan
D. Inhibit DNA gyrase in the bacteria
E. Bind to ergosterol from pores resulting in linkage of cellular
Which of the following is one of the most common side effects of vancomycin?
A. Ototoxicity
B. Disulfiram like side effect
C. Diarrhea
D. Weight gain
E. Hallucinations
Treatment of large intestine infection mainly caused by food intoxication may include:
I- Lots of fluids II- Ciprofloxacin III- Metronidazole
A. I only
B. III only
C. I and II only
D. II and III only
E. All are correct
Colitis associated with antibiotic use can best be treated by:
A. Cephalosporins
B. Macrolides
C. Aminoglycosides
D. Vancomycin
E. Penicillin
Antibiotics that often cause colitis-acute inflammation of colon as side effect include:
I- Broad-spectrum penicillins II- Cephalosporins III- Clindamycin
A. I only
B. III only
C. I and II only
D. II and III only
E. All are correct
Drug used together with chloroquine in the treatment of malaria with the purpose to kill persistants parasites in the liver of a person infected with Plasmodium vivax is:
A. Quinine
B. Pyrimethamine
C. Sulfadoxine
D. Primaquine
E. Quinidine
Patient is resistant to chloroquine and need to be treated for malaria. Which of the following drugs or combination should be more appropriate for this patient?
A. Atovaquone only
B. Chloroquine and primaquine
C. Quinine and doxacycline
D. Mefloquine
E. C and D are correct
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